prof. dr. ir. De Mey Marjan
Microbial production hosts such as E.coli and yeast are optimized for specialized plant metabolites through the merging of metabolic engineering and modelling, synthetic and system biology.
Complex specialized plant metabolites include hundreds of thousands of unique small molecules, which are bioactive and of which many exhibit beneficial applications for humans. Currently, these molecules are extracted from plants, which is tedious, very labour-intensive and typically yields low titres. Industrial biotechnology provides an economically very interesting alternative. Microbial production hosts such as E. coli and yeast are optimized for the production of specialized plant metabolites through merging of cutting-edge technologies such as metabolic engineering and modelling, synthetic biology and system biology.
Development of cost-effective biotech production processes for specialized plant metabolites enabling the market to access products with a myriad of applications in -among others- pharmaceuticals, food additives, and cosmetics.