prof. dr. ir. De Mey Marjan
An increase in the speed and cost-effectiveness of rational and systematic engineering will boost industrial biotechnology and facilitate the necessary transition to a sustainable bio-based economy.
The promise of metabolic engineering, in concert with synthetic and systems biology, is to smoothen the transition of our fossil-fuel based economy to a more bio-based economy by providing novel tools and technologies to convert renewable resources into a broad range of bio-products, bio-materials and bio-energy in a rational and standardized manner. We focus on the development of novel tools and methods to fine tune metabolic pathways for the biosynthesis of chemicals and fuels. These novel tools include several DNA parts libraries as well as efficient and rapid methods for constructing synthetic pathways and for high-throughput screening by developing biosensors. We apply these tools to create custom designed microbes for the production of useful chemicals from renewable resources.
Development of novel tools enabling rational and systematic engineering. The resulting acceleration in development times and reduction of development cost of bioprocesses will in turn boost industrial biotechnology and facilitate the transition to a sustainable bio-based economy.